Time Restricted Eating on Human Health Part 4 - Metabolic Effects | Modern Manual Therapy Blog - Manual Therapy, Videos, Neurodynamics, Podcasts, Research Reviews

Time Restricted Eating on Human Health Part 4 - Metabolic Effects

Time Restricted Eating on Human Health Part 4 - Metabolic Effects - themanualtherapist.com


Effects of Time Restricted Eating on Human Health
SERIES (4/6)

METABOLIC EFFECTS:
Intermittent fasting can have beneficial metabolic effects via caloric restriction.

This review confirmed this with the following findings:

  • Avg weight loss of 3% and fat mass reduction.
  • Body fat loss and a decrease in the level of fasting glucose concentration.
  • Weight loss and BMI reduction.
  • Drop in systolic blood pressure.
  • Reduction in waist circumference and a decrease in cholesterol concentration.

6/10 studies showed beneficial metabolic effects, regardless of the calorie restriction. For example, a randomized iso-caloric study evaluating eTRE showed a decrease in the average blood sugar level and reduced insulin resistance. Likewise, a crossover randomized trial demonstrated that short-term TRE improved nocturnal glycemic control.

An iso-caloric trial on eTRE 8/16 showed an improvement in glucose tolerance and a major decrease in systolic blood pressure, comparable to the results obtained with pharmacological treatment with an ACE inhibitor.

Moro et al. showed a combination of TRE 8/16 with regular physical activity:
  • Reduced fat mass.
  • Decreased blood glucose levels.
  • Improved insulin resistance.
  • & Lowered triglyceride levels.
Some suggest these effects are due to the increase in adiponectin levels.

Adiponectin is an adipokine, which increases during fasting and could produce a loss of fat mass by increasing energy expenditure.

Adiponectin also activates AMPK, a kinase which stimulates lipolysis and insulin-sensitivity.

Although metabolic changes are the result of an imbalance between the energy content of food eaten and energy expended partly via physical activity, only 3 studies measured physical activity.

However due to limitations and bias, further studies on TRE controlling the impact of physical activity can confirm these effects.

NEXT UP:
5. Effects on Circadian Clock and Other.
6. Conclusions

SOURCE:
Adafer et al. 2020. Food Timing, Circadian Rhythm and Chrononutrition: A Systematic Review of Time-Restricted Eating.

Dalton Urrutia, MSc PT

Dalton is a Physical Therapist from Oregon, currently living and running the performance physiotherapy clinic he founded in London for Grapplers and Strength & Conditioning athletes. Dalton runs the popular instagram account @physicaltherapyresearch, where he posts easy summaries of current and relevant research on health, fitness, and rehab topics. 
Want to learn more or contact him?
Reach out online:
@Grapplersperformance


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